In silico optimization of lipid production in Rhodosporidium toruloides by gene knockout strategies
نویسندگان
چکیده
منابع مشابه
Lipid production by Rhodosporidium toruloides Y2 in bioethanol wastewater and evaluation of biomass energetic yield.
The oleaginous yeast Rhodosporidium toruloides Y2 was employed to remove waste nutrients from bioethanol wastewater while simultaneously producing biomass enriched in microbial lipids. Under optimal conditions, the COD degradation ratio, biomass and lipid content reached 72.3%, 3.8 g/l and 34.9%, respectively. For accelerating biomass and lipid accumulation, different feeding strategies of subs...
متن کاملEnhanced lipid production by Rhodosporidium toruloides using different fed-batch feeding strategies with lignocellulosic hydrolysate as the sole carbon source
BACKGROUND Industrial biotechnology that is able to provide environmentally friendly bio-based products has attracted more attention in replacing petroleum-based industries. Currently, most of the carbon sources used for fermentation-based bioprocesses are obtained from agricultural commodities that are used as foodstuff for human beings. Lignocellulose-derived sugars as the non-food, green, an...
متن کاملThe Production, Regulation and Extraction of Carotenoids from Rhodosporidium toruloides
Carotenoids are valuable pigments of commercial interest for various health benefits. There is rising demand for natural carotenoids from microorganisms, although the majority of industrially produced carotenoids are currently chemically synthesized. Rhodosporidium toruloides is oleaginous red yeast, which can produce large amounts of carotenoids and lipids simultaneously. It is also able to as...
متن کاملMetabolic network analysis and experimental study of lipid production in Rhodosporidium toruloides grown on single and mixed substrates
BACKGROUND Microbial lipids (triacylglycerols, TAG) have received large attention for a sustainable production of oleochemicals and biofuels. Rhodosporidium toruloides can accumulate lipids up to 70% of its cell mass under certain conditions. However, our understanding of lipid production in this yeast is still much limited, especially for growth with mixed substrates at the level of metabolic ...
متن کاملLipid production in batch and fed-batch cultures of Rhodosporidium toruloides from 5 and 6 carbon carbohydrates
BACKGROUND Microbial lipids are a potential source of bio- or renewable diesel and the red yeast Rhodosporidium toruloides is interesting not only because it can accumulate over 50% of its dry biomass as lipid, but also because it utilises both five and six carbon carbohydrates, which are present in plant biomass hydrolysates. METHODS R. toruloides was grown in batch and fed-batch cultures in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: IFAC-PapersOnLine
سال: 2019
ISSN: 2405-8963
DOI: 10.1016/j.ifacol.2019.06.043